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Artículo de investigación

Impact of the Glucolipotoxicity In vivo and Insulinotoxicity Inducing in Fibroblast Aortic of Sand Rat (Psammomys obesus)

Smail Leila, Berdja Sihem, Neggazi Samia, Hamlat Nadjiba, Boumaza Saliha, Sahraoui Abdelhamid, Benazzoug Yasmina, Kacimi Ghouti, Haffaf E Mahdi and Aouichat Bouguerra Souhila

It was established that the sand rat Psammomys obesus is an experimental model of type diabetes 2 and dyslipidemia, in this in vivo study the sand rats were submitted to natural..Ver más»

Comentario

Determining The Cause And Manner Of Death

Charles Petty

In cases of suspicious death, a forensic pathologist is charged with determining the cause and manner of death. In the United States, each state has its own regulations that gov..Ver más»

Artículo de investigación

Luteolin-7-O-Glycosides from the Leaves of Centropogon cornutus (Campanulaceae)

Powder-George YL

A new luteolin-7-O-glycoside, named Centropogin A (1), together with three known luteolin-7-O-glycosides, Luteolin- 7-O-xyloside (2), Luteolin-..Ver más»

Perspectiva

Mechanistic Insights and Translational Relevance of Targeting HSP90 as a Novel Therapy for Cancer

Elena Johnson

A highly conserved molecular chaperon called Heat Shock Protein (HSP90) is required for the maturation of freshly generated polypeptides and offers a haven for the refolding or ..Ver más»

Artículo de investigación

Differential Cytokine Release from Brain Microvascular Endothelial Cells Treated with Dexamethasone and Multiple Sclerosis Patient Sera

Malgorzata Burek, Aiden Haghikia, Ralf Gold, Norbert Roewer, Andrew Chan and Carola Y Förster

Objective: Multiple sclerosis (MS) is a neurodegenerative disorder of the central nervous system (CNS). Damage of the blood-brain barrier integrity is a key pat..Ver más»

Editorial

Locus Chemotherapy in Cancer Angiogenesis

Ziv Radisavljevic

A cancer angiogenesias is a complex system. Its robustness is supported by the signaling elements from cancer hypoxic microenvironment. The signaling angiogenic networks have no..Ver más»