Vincent King
The most prevalent monogenic cause of ESKD, Autosomal Dominant Polycystic Kidney Disease (ADPKD), is characterised by hypertension, the persistent development of kidney cysts, and the degeneration of the kidney parenchyma. Significant progress has been made in recent years in terms of the diagnosis, prognosis, and understanding of the pathophysiology and course of the disease. There is currently no renal condition where nephronprotective measures are more appropriate. Implementing these methods and referring patients to nephrology early may have a significant impact. Total kidney volume is a useful prognostic indicator that categorises patients into groups with slow or rapid disease progression, which has consequences for their care. It is possible to measure the total kidney volume, categorise the condition, and predict the outcome using widely accessible equipment.