Carol Williams
Rats were given dihydrotachysterol and furosemide at the same time to examine the effect of Sal uretic drugs on hypercalcemia. Simultaneous furosemide therapy reduced the high serum calcium level of dihydrotachysterol. Furosemide was used alone to temporarily lower a normal calcemic blood level. The best explanation for furosemide's lowering of hypercalcemic blood levels is an increase in calcium excretion. There was a consistent reduction in serum sodium. To avoid extracellular volume contraction and maintain enhanced calcium excretion, sodium and fluid losses were continually replenished. The phosphorus level in the blood was momentarily raised, while the magnesium and potassium levels remained unaltered. Hypercalcemia was efficiently treated with furosemide, according to clinical findings.